Plant Transcription Factor Database
Previous version: v3.0
Spinacia oleracea
WRKY Family
Species TF ID Description
Sp_003610_afga.t1WRKY family protein
Sp_004170_asdt.t1WRKY family protein
Sp_006240_topm.t1WRKY family protein
Sp_009720_kgso.t1WRKY family protein
Sp_010850_ckzq.t1WRKY family protein
Sp_011540_epwz.t1WRKY family protein
Sp_014630_xyza.t1WRKY family protein
Sp_030320_sppf.t1WRKY family protein
Sp_030320_sppf.t2WRKY family protein
Sp_033230_yrso.t1WRKY family protein
Sp_039590_pigj.t1WRKY family protein
Sp_039640_dehz.t1WRKY family protein
Sp_044260_cngh.t1WRKY family protein
Sp_046520_nxcc.t1WRKY family protein
Sp_046520_nxcc.t2WRKY family protein
Sp_052830_dptr.t1WRKY family protein
Sp_060420_defs.t1WRKY family protein
Sp_060460_fefj.t1WRKY family protein
Sp_066780_khjy.t1WRKY family protein
Sp_071530_ehan.t1WRKY family protein
Sp_072020_rukc.t1WRKY family protein
Sp_080250_frhe.t1WRKY family protein
Sp_087120_apwf.t1WRKY family protein
Sp_089450_rdgt.t1WRKY family protein
Sp_089450_rdgt.t2WRKY family protein
Sp_090720_poet.t1WRKY family protein
Sp_106280_aywm.t1WRKY family protein
Sp_107410_ucwr.t1WRKY family protein
Sp_110580_qepk.t1WRKY family protein
Sp_110710_zzug.t1WRKY family protein
Sp_111800_fumr.t1WRKY family protein
Sp_111800_fumr.t2WRKY family protein
Sp_117510_ahuq.t1WRKY family protein
Sp_126230_mwhz.t1WRKY family protein
Sp_126230_mwhz.t2WRKY family protein
Sp_162090_wpom.t1WRKY family protein
Sp_164900_izqw.t1WRKY family protein
Sp_166080_roit.t1WRKY family protein
Sp_172520_tiqt.t1WRKY family protein
Sp_175350_uqhr.t1WRKY family protein
Sp_178170_ufup.t1WRKY family protein
Sp_180300_cyek.t1WRKY family protein
Sp_188130_fecz.t1WRKY family protein
Sp_190610_kzew.t1WRKY family protein
Sp_195750_urxy.t1WRKY family protein
Sp_196780_fijm.t1WRKY family protein
Sp_196780_fijm.t2WRKY family protein
Sp_213430_epsk.t1WRKY family protein
WRKY Family Introduction

WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and de-repression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.

The defining feature of WRKY transcription factors is their DNA binding domain. This is called the WRKY domain after the almost invariant WRKY amino acid sequence at the N-terminus. In a few WRKY proteins, the WRKY amino acid sequences have been replaced by WRRY, WSKY, WKRY, WVKY or WKKY. The WRKY domain is about 60 residues in length, and as well as containing the WRKY signature it also has an atypical zinc-finger structure at the C-terminus. The zinc-finger structure is either Cx4-5Cx22-23HxH or Cx7Cx23HxC. Initially, in the absence of a complete gene family from any plant species, the WRKY transcription factors were divided into three groups based on the number of WRKY domains (two domains in Group I proteins and one in the others) and the structure of their zinc fingers (C2HC in Group III proteins).

Rushton PJ, Somssich IE, Ringler P, Shen QJ.
WRKY transcription factors.
Trends Plant Sci, 2010. 15(5): p. 247-58.
PMID: 20304701